What is the prognosis of H1N1 influenza (swine flu)?

Updated: Apr 09, 2019
  • Author: Michael Stuart Bronze, MD; Chief Editor: Russell W Steele, MD  more...
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Answer

A review of medical records from the 2009 US pandemic found hospitalized patients with pandemic H1N1 and pneumonia were at risk for severe outcomes including ARDS, sepsis, and death. However, patients often received delayed antiviral treatment (>2 days after illness onset). Patients with H1N1 and pneumonia should receive early and aggressive treatment with antibiotics and influenza antiviral agents. [47]

In a multicenter study in Britain consisting of over 1,500 patients, independent predictors of severe outcome included age 55-64 years, certain chronic lung diseases, underlying neurological disease, obesity, delayed admission (≥5 days after illness onset), pneumonia, and others. [48]


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