Are antispasmodics effective in the treatment of irritable bowel syndrome (IBS)?

Updated: Dec 11, 2019
  • Author: Jenifer K Lehrer, MD; Chief Editor: BS Anand, MD  more...
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Answer

A systematic review found that several antispasmodics, including peppermint oil, pinaverium, trimebutine, and cimetropium/dicyclomine, significantly outperformed placebo at improving irritable bowel syndrome symptom and global assessment scores. [33] Pinaverium and cimetropium are not available in the United States. The National Institutes of Health's (NIH's) National Center for Complementary and Integrative Health (NCCIH) provides information regarding a small amount of research that suggests peppermint oil may improve IBS symptoms. [4]


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