Which history-specific studies are used for the diagnosis of irritable bowel syndrome (IBS)?

Updated: Dec 11, 2019
  • Author: Jenifer K Lehrer, MD; Chief Editor: BS Anand, MD  more...
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History-specific studies include the following:

  • Hydrogen breath testing to exclude bacterial overgrowth in patients with diarrhea and to screen for lactose and/or fructose intolerance

  • Tissue transglutaminase antibody testing and small bowel biopsy in IBS-D to diagnose celiac disease.

  • Thyroid function tests

  • Serum calcium testing to screen for hyperparathyroidism

  • Erythrocyte sedimentation rate and C-reactive protein measurement are nonspecific screening tests for inflammation

See Workup for more detail.

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