What other laboratory tests have a role in the evaluation of peritonitis and abdominal sepsis?

Updated: Jul 23, 2019
  • Author: Brian J Daley, MD, MBA, FACS, FCCP, CNSC; Chief Editor: Praveen K Roy, MD, AGAF  more...
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Procalcitonin level

Findings from a 2019 retrospective study (2016-2017) of 99 patients with abdominal sepsis suggests that serum procalcitonin level can be an indicator of severity and mortality in abdominal sepsis due to secondary peritonitis. [18] There appeared to be statistical significance with a procalcitonin level above 10.1 mcg/L, Mannheim peritonitis score over 26 points, controlling nutritional status (CONUT) score above 6 points, and the presence of organic faults, but not with APACHE (Acute Physiology and Chronic Health Evaluation) and SOFA (Sequential Organ Failure Assessment) scores and mortality. [18]


A urinalysis is used to rule out urinary tract diseases (eg, pyelonephritis, renal stone disease); however, patients with lower abdominal and pelvic infections often demonstrate white blood cells (WBCs) in the urine and microhematuria.

Stool sample

In patients with diarrhea, evaluate a stool sample—employing a Clostridium difficile toxin assay, a WBC count, and a specific culture (ie, Salmonella, Shigella, cytomegalovirus [CMV])—if the patient's history suggests infectious enterocolitis.

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