Which factors have reduced morbidity and mortality of intra-abdominal sepsis?

Updated: Jul 23, 2019
  • Author: Brian J Daley, MD, MBA, FACS, FCCP, CNSC; Chief Editor: Praveen K Roy, MD, AGAF  more...
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Over the past decade, the combination of better antibiotic therapy, more aggressive intensive care, and earlier diagnosis and therapy with a combination of operative and percutaneous techniques have led to a significant reduction in morbidity and mortality related to intra-abdominal sepsis.

Independent risk factors of the intra-abdominal view (IAV) for severe complicated intra-abdominal sepsis (SCIAS) or 30-day mortality appear to be the extent of peritonitis, diffuse substantial redness of the peritoneum, type of exudate (fecal or bile), and a nonappendiceal source of the infection. [12]

In general, there is a 6% overall mortality in secondary peritonitis, rising to 35% in those who develop sepsis. [9]

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