What is the probability of progression of ulcerative colitis (UC)?

Updated: Apr 10, 2020
  • Author: William A Rowe, MD; Chief Editor: BS Anand, MD  more...
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Patients with ulcerative colitis limited to the rectum and sigmoid have a 50% chance of progressing to more extensive disease over 10 years [49] and a 7.5% rate of colectomy over 5 years. [50] Approximately 10% of patients presenting with proctitis will develop a pancolitis. [49, 50]

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