What are treatment options for Gilbert syndrome?

Updated: May 21, 2019
  • Author: Hisham Nazer, MBBCh, FRCP, DTM&H; Chief Editor: BS Anand, MD  more...
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Answer

Once the diagnosis of Gilbert syndrome is established, the most important aspect of treatment is reassurance. The clinician must make it perfectly clear to the patient that the syndrome is essentially benign, is not associated with increased morbidity (except for an increased incidence of side effects from certain drugs, such as the antitumor agent irinotecan), has an excellent prognosis, and is associated with normal life expectancy. In light of the benign and inconsequential nature of Gilbert syndrome, the use of medications to treat patients with this condition is unjustified in clinical practice.


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