What other causes of jaundice should be included in the differential diagnoses for infants with unconjugated hyperbilirubinemia?

Updated: May 21, 2019
  • Author: Hisham Nazer, MBBCh, FRCP, DTM&H; Chief Editor: BS Anand, MD  more...
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Answer

Although no specific test exists for physiologic jaundice, other causes of jaundice should be considered in infants with one or more of the following:

  • Jaundice occurring within 24 hours of birth

  • Serum concentrations of unconjugated bilirubin of 11-12 mg/dL in infants who are formula-fed or 14-15 mg/dL in infants who are breastfed

  • Increased levels of conjugated bilirubin (>2 mg/dL)

  • Jaundice persisting for more than 2 weeks


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