What is the incidence of unconjugated hyperbilirubinemia in the US?

Updated: May 21, 2019
  • Author: Hisham Nazer, MBBCh, FRCP, DTM&H; Chief Editor: BS Anand, MD  more...
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Answer

There have been less than 50 known cases of Crigler-Najjar syndrome in the United states, and only a few hundred cases have been described in the world literature. [46] In the United States, the prevalence of Gilbert syndrome is 3%-7%.

Breast milk jaundice affects approximately 0.5%-2.4% of live births. There is a familial incidence of 13.9%, indicating that, in some cases, a unique genetic factor may be expressed.


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