Which medications in the drug class Sympathomimetic agents are used in the treatment of Hepatorenal Syndrome?

Updated: Oct 16, 2017
  • Author: Deepika Devuni, MD; Chief Editor: BS Anand, MD  more...
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Sympathomimetic agents

Improve renal artery perfusion.

Dopamine (Intropin)

Stimulates both adrenergic and dopaminergic receptors. Hemodynamic effect is dependent on dose. Lower doses predominantly stimulate dopaminergic receptors, which, in turn, produce renal and mesenteric vasodilation. Cardiac stimulation and renal vasodilation are produced by higher doses. Described for its historical interest because it has no role in monotherapy for HRS. However, reversal of HRS has been described when used at low doses in conjunction with ornipressin.

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