What is the role of pentoxifylline in the prevention of hepatorenal syndrome (HRS)?

Updated: Oct 16, 2017
  • Author: Deepika Devuni, MD; Chief Editor: BS Anand, MD  more...
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Answer

In patients with acute alcoholic hepatitis, one study reported that the administration of pentoxifylline (400 mg tid for 28 d) reduced the incidence of HRS and mortality rates (8% and 24%, respectively) compared with a placebo group (35% and 46%, respectively). However, no long-term data exist on renal function or mortality rates in these patients.


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