What is the relationship between large-volume paracentesis (LVP) and hepatorenal syndrome (HRS)?

Updated: Oct 16, 2017
  • Author: Deepika Devuni, MD; Chief Editor: BS Anand, MD  more...
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Answer

LVP is considered another risk factor for the development of HRS, which may be prevented by the administration of albumin.

Patients who have cirrhosis with ascites have a 10% chance of developing HRS at 1 year and a 40% chance at 5 years. One alternative to treatment aimed at preventing HRS is performing liver transplantation in these patients before HRS develops, particularly because risk factors for the development of HRS have been identified. With the current donor shortage, this does not seem to be a realistic possibility.


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