What is the role of the molecular adsorbent recirculating system (MARS) in the treatment of hepatorenal syndrome (HRS)?

Updated: Oct 16, 2017
  • Author: Deepika Devuni, MD; Chief Editor: BS Anand, MD  more...
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Answer

Variations of hemodialysis include the molecular adsorbent recirculating system. [9] This is a modified dialysis method that uses an albumin-containing dialysate that is recirculated and perfused online through charcoal- and anion-exchanger columns. A prospective, randomized, controlled trial showed improvement of type 1 HRS with this method, although long-term survival remained very poor, with survival of more than 1 month in only 1 of 8 patients in the treatment arm.

If transplantation is not available, hemodialysis probably will continue to be performed for patients on the waiting list.


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