When are urinalysis and urine electrolytes studies indicated in the workup of hepatorenal syndrome (HRS)?

Updated: Oct 16, 2017
  • Author: Deepika Devuni, MD; Chief Editor: BS Anand, MD  more...
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Significant proteinuria or hematuria may provide a clue that an organic cause may be responsible for patients' renal failure. Similarly, urinary tract infection may be detected, and this usually is readily treatable.

Measuring urine sodium and creatinine levels is used as a screening test to assess the degree of sodium retention. Patients with low urine sodium excretion (<5 mEq/L) are at a greater risk of developing HRS. Urine sodium and creatinine levels are also used to calculate the fractional excretion of sodium, which is helpful in differentiating HRS and prerenal azotemia from intrinsic renal disease.

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