Which medications in the drug class Thrombopoietin-Receptor Agonists are used in the treatment of Hepatitis C?

Updated: Oct 07, 2019
  • Author: Vinod K Dhawan, MD, FACP, FRCPC, FIDSA; Chief Editor: BS Anand, MD  more...
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Answer

Thrombopoietin-Receptor Agonists

These agents directly stimulate bone marrow platelet production to provide stable platelet counts to allow therapy with interferons.

Eltrombopag (Promacta)

Oral thrombopoietin (TPO) receptor agonist. Interacts with transmembrane domain of human TPO receptor and induces megakaryocyte proliferation and differentiation from bone marrow progenitor cells. This agent is indicated for the treatment of thrombocytopenia in patients with chronic hepatitis C to allow the initiation and maintenance of interferon-based therapy.


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