What are the treatment guidelines for chronic HCV infection in genotype 3 patients without cirrhosis previously treated with PEG-IFN/ribavirin?

Updated: Oct 07, 2019
  • Author: Vinod K Dhawan, MD, FACP, FRCPC, FIDSA; Chief Editor: BS Anand, MD  more...
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Answer

HCV genotype 3 PEG-IFN/ribavirin treatment-experienced patients without cirrhosis

Recommended regimen

  • Daily fixed-dose combination of sofosbuvir (400 mg)/velpatasvir (100 mg) for 12 weeks

Alternative regimens

  • Daily fixed-dose combination of glecaprevir (300 mg)/pibrentasvir (120 mg) for 16 weeks
  • Daily fixed-dose combination of sofosbuvir (400 mg)/velpatasvir (100 mg)/voxilaprevir (100 mg) for 12 weeks when Y93H is present

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