Which direct-acting antiviral agents (DAAs) are currently available for the treatment of hepatitis C (hep C) infection?

Updated: Oct 07, 2019
  • Author: Vinod K Dhawan, MD, FACP, FRCPC, FIDSA; Chief Editor: BS Anand, MD  more...
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Answer

Currently available agents and their target sites are outlined below.

NS3/4 targeting protease inhibitors

  • Simeprevir
  • Paritaprevir
  • Grazoprevir
  • Glecaprevir

NS5B targeting polymerase inhibitors

  • Nucleotide: Sofosbuvir
  • Non-nucleotide: Dasabuvir

NS5A targeting agents

  • Ledipasvir
  • Ombitasvir
  • Elbasvir
  • Velpatasvir
  • Pibrentasvir

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