What are the racial predilections for hepatitis C virus (HCV) infection?

Updated: Oct 07, 2019
  • Author: Vinod K Dhawan, MD, FACP, FRCPC, FIDSA; Chief Editor: BS Anand, MD  more...
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Answer

In the United States, HCV infection is more common among minority populations, such as black and Hispanic persons in association with lower economic status and educational levels. In addition, in the United States, genotype 1 is more prevalent in black individuals than in other racial groups.

Racial disparity has also been reported in the all-cause mortality in patients with HCV infection. A 2017 National Health and Nutrition Examination Survey (NHANES) III report found that having chronic HCV was associated with a 2.63-fold higher all-cause mortality rate ratio (MRR) compared with being HCV negative. [30] The highest MRR of having chronic HCV compared to being HCV negative was 7.48 among Mexican Americans, 2.67 among non-Hispanic white persons, and 2.02 among non-Hispanic black persons. Mexican Americans with chronic HCV had approximately a seven-fold higher mortality than HCV-negative individuals. [30]


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