What is the role of hepatitis C (hep C) in the etiology of chronic liver disease?

Updated: Oct 07, 2019
  • Author: Vinod K Dhawan, MD, FACP, FRCPC, FIDSA; Chief Editor: BS Anand, MD  more...
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Answer

Because most patients infected with HCV have chronic liver disease, which can progress to cirrhosis and HCC, chronic infection with HCV is one of the most important causes of chronic liver disease (see the image below) and, according to a report by Davis et al, the most common indication for orthotopic liver transplantation (OLT) in the United States. [10]

Hepatitis C. Causes of chronic liver disease. Cour Hepatitis C. Causes of chronic liver disease. Courtesy of the US Centers for Disease Control and Prevention.

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