What are the WHO recommendations for monitoring for hepatitis B (HBV) (Hep B) progression?

Updated: Jun 08, 2021
  • Author: Nikolaos T Pyrsopoulos, MD, PhD, MBA, FACP, AGAF; Chief Editor: BS Anand, MD  more...
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The WHO recommends yearly monitoring at a minimum of the following (strong recommendation):

  • Levels of ALT (and AST level for APRI), HBsAg, HBeAg, and HBV DNA (where HBV DNA testing is available)
  • Liver fibrosis, in those without baseline cirrhosis, using noninvasive studies such as APRI score or FibroScan
  • Treatment adherence during therapy, at regular intervals and at each visit

More frequent monitoring may be indicated in certain individuals (Conditional recommendations)

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