According to the WHO recommendations, which patients with hepatitis B (HBV) (Hep B) require lifelong nucleos(t)ide analog (NA) therapy?

Updated: Aug 01, 2018
  • Author: Nikolaos T Pyrsopoulos, MD, PhD, MBA, FACP, AGAF; Chief Editor: BS Anand, MD  more...
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Answer

All individuals with cirrhosis based on clinical evidence (or APRI score >2 in adults) require lifelong NA therapy. Antiviral therapy in these individuals should not be discontinued owing to the potential for HBV reactivation.


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