How effective is the hepatitis B (HBV) (Hep B) 3-dose vaccine series when administered in infancy?

Updated: Aug 01, 2018
  • Author: Nikolaos T Pyrsopoulos, MD, PhD, MBA, FACP, AGAF; Chief Editor: BS Anand, MD  more...
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Answer

In a report that collected data from 2 studies assessing the 5- and 10-year persistence of anti-HBs and immune response to a hepatitis B virus (HBV) vaccine challenge in children and adolescents who had received the HBV 3-dose vaccine series in infancy, German investigators demonstrated that this routine practice induced long-term anti-HBs persistence for 10 years and immune memory against HBV—even with waning anti-HBs levels. [96]


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