What does the hepatitis B (HBV) (Hep B) vaccine consist of?

Updated: Jun 08, 2021
  • Author: Nikolaos T Pyrsopoulos, MD, PhD, MBA, FACP, AGAF; Chief Editor: BS Anand, MD  more...
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Although a limited number of medications can be used to treat chronic hepatitis B, vaccination is a safe and effective prevention strategy. [98] Universal hepatitis B vaccination programs are ongoing in endemic areas, with encouraging results. The hepatitis B vaccine (HepB) consists of recombinant hepatitis B surface antigen (HBsAg) produced in yeast. A series of 3 injections may achieve HBsAg antibody (anti-HBs) levels greater than 10 million IU/mL in approximately 95% of vaccinated individuals. Vaccination with a single dose must be repeated every 5-10 years.

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