What are the guidelines for reducing the risk of perinatal hepatitis B (HBV) (Hep B) transmission?

Updated: Jun 08, 2021
  • Author: Nikolaos T Pyrsopoulos, MD, PhD, MBA, FACP, AGAF; Chief Editor: BS Anand, MD  more...
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The 2016 American Association for the Study of Liver Diseases (AASLD) has similar guidelines for the treatment of chronic hepatitis B in pregnant women. [38]  The AASLD suggests antiviral therapy to reduce the risk of perinatal HBV transmission in HBsAg-positive pregnant women with an HBV DNA level above 200,000 IU/mL. (Conditional recommendation) Infants of these mothers should receive immunoprophylaxis according to current World Health Organization and Centers for Disease Control and Prevention recommendations.

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