What is the role of telbivudine in the treatment of hepatitis B (HBV) (Hep B)?

Updated: Aug 01, 2018
  • Author: Nikolaos T Pyrsopoulos, MD, PhD, MBA, FACP, AGAF; Chief Editor: BS Anand, MD  more...
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Answer

Telbivudine, a cytosine nucleoside analogue, is a second-line agent (not preferred) used in HBV therapy. [19]  This drug is a potent inhibitor of HBV DNA polymerase. Although telbivudine appears to have slightly more potent antiviral activity than do adefovir and lamivudine, it is more expensive and plays a limited role in primary therapy.


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