Which antiviral drug has been used for the treatment of polyarteritis nodosa (PAN) in patients with hepatitis B (HBV) (Hep B)?

Updated: Aug 01, 2018
  • Author: Nikolaos T Pyrsopoulos, MD, PhD, MBA, FACP, AGAF; Chief Editor: BS Anand, MD  more...
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Answer

The antiviral drug adenine arabinoside and IFN-a have been used in conjunction with plasmapheresis and a short course of corticosteroids, with promising results.

The combination of short-term corticosteroids accompanied by plasmapheresis and lamivudine, as used in one study, resulted in 100% clinical recovery and 66% seroconversion, although the number of patients in the trial was relatively small. [69]


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