According to the NIH, when is therapy for hepatitis B (HBV) (Hep B) not routinely indicated?

Updated: Jun 08, 2021
  • Author: Nikolaos T Pyrsopoulos, MD, PhD, MBA, FACP, AGAF; Chief Editor: BS Anand, MD  more...
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The NIH also indicates that immediate therapy is not routinely indicated for patients who have the following [2] :

  • Chronic hepatitis B with high levels of serum HBV DNA but normal serum ALT levels or little activity on liver biopsy (immune-tolerant phase)

  • Low levels of or no detectable serum HBV DNA and normal serum ALT levels (inactive chronically infected/low replicative phase)

  • Positive serum HBV DNA but not HBsAg (latent HBV infection), unless the patient is undergoing immunosuppression

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