When is therapy indicated for the treatment of hepatitis B (HBV) (Hep B)?

Updated: Jun 08, 2021
  • Author: Nikolaos T Pyrsopoulos, MD, PhD, MBA, FACP, AGAF; Chief Editor: BS Anand, MD  more...
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Answer

Therapy is currently recommended for patients with evidence of chronic active hepatitis B disease (ie, abnormal aminotransferase levels, positive HBV DNA findings, positive or negative hepatitis B e antigen [HBeAg]). Various algorithms have been proposed, such as that by the American Association for the Study of Liver Diseases (AASLD), [38, 56] the European Association for the Study of the Liver (EASL), [57] the Asian Pacific Association for the Study of the Liver (APASL), [58] the Canadian Association for the Study of the Liver (CASL), [59] the National Institute for Health and Clinical Excellence (NICE), [60] Kuo and Gish, [19] and Keeffe et al. [61]


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