Is ultrasonographic surveillance for the detection of hepatocellular carcinoma (HCC) effective in patients with cirrhosis due to hepatitis B (HBV) (Hep B) infection?

Updated: Aug 01, 2018
  • Author: Nikolaos T Pyrsopoulos, MD, PhD, MBA, FACP, AGAF; Chief Editor: BS Anand, MD  more...
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Answer

In a trial that compared ultrasonographic surveillance at 3- or 6-month intervals to detect hepatocellular carcinoma (HCC) in 1278 patients with cirrhosis due to hepatitis B virus (12.5%), hepatitis C virus (44.1%), or alcohol (39.2%), investigators reported that ultrasonographic surveillance at 3-month intervals detected more small focal lesions (≤10 mm) than at 6-month intervals; however, the shorter interval did not improve detection of small HCC. [50]


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