What are the USPSTF recommendations for screening asymptomatic adolescents and adults at high risk for hepatitis B (HBV) (Hep B) infection?

Updated: Jun 08, 2021
  • Author: Nikolaos T Pyrsopoulos, MD, PhD, MBA, FACP, AGAF; Chief Editor: BS Anand, MD  more...
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In June 2014, the US Preventive Services Task Force (USPSTF), which had previously recommended against screening asymptomatic persons for HBV infection, issued a recommendation in favor of screening of asymptomatic, nonpregnant adolescents and adults at high risk for HBV infection, including the following [43, 44, 45, 46] :

  • Those born in countries and regions where prevalence of HBV infection is at least 2%

  • Individuals born in the United States who were not vaccinated as infants and whose parents were born in regions with a high prevalence of HBV infection, such as sub-Saharan Africa and southeast and central Asia

  • HIV-positive individuals

  • Injection drug users

  • Men who have sex with men

  • Household contacts of individuals with HBV infection

Testing should be performed with a HBsAg test followed by a licensed, neutralizing confirmatory test for initially reactive screening results. [43, 44, 45, 46]

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