How frequently does membranous glomerulonephritis (MGN) undergo spontaneous remission in patients with hepatitis B (HBV) (Hep B) infection?

Updated: Aug 01, 2018
  • Author: Nikolaos T Pyrsopoulos, MD, PhD, MBA, FACP, AGAF; Chief Editor: BS Anand, MD  more...
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Answer

Approximately 30-60% of cases with MGN undergo spontaneous remission. However, the course of HBV-related membranous nephropathy in adults in areas in which the virus is endemic is not benign. Regardless of treatment, hepatitis B disease has a slow, but relentlessly progressive, clinical course in approximately one third of patients, resulting in progressive renal failure and necessitating maintenance dialysis therapy.


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