How common is chronic hepatitis B (HBV) (Hep B) in children and adults?

Updated: Aug 01, 2018
  • Author: Nikolaos T Pyrsopoulos, MD, PhD, MBA, FACP, AGAF; Chief Editor: BS Anand, MD  more...
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Answer

In immunocompetent adults, less than approximately 4% of HBV infections become chronic, whereas up to 90% of perinatally infected infants will have chronic disease. [8] Among children who acquire HBV infection between ages 1 and 5 years, 30-50% become chronically infected. According to the World Health Organization (WHO), by the end of 2010, the HBV vaccine had been routinely introduced in 179 countries, with a global coverage of 75%. Coverage in the Americas was at 89%; in Europe, 78%; in Africa, 76%; and in Southeast Asia, 52%. [9]


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