Which lab tests may be used to assess the stages of hepatitis B (HBV) (Hep B)?

Updated: Jun 08, 2021
  • Author: Nikolaos T Pyrsopoulos, MD, PhD, MBA, FACP, AGAF; Chief Editor: BS Anand, MD  more...
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The following laboratory tests may be used to assess the various stages of hepatitis B disease:

  • Alanine aminotransferase and/or aspartate aminotransferase levels

  • Alkaline phosphatase levels

  • Gamma-glutamyl transpeptidase levels

  • Total and direct serum bilirubin levels

  • Albumin level

  • Hematologic and coagulation studies (eg, platelet count, complete blood count [CBC], international normalized ratio)

  • Ammonia levels

  • Erythrocyte sedimentation rate

  • Serologic tests

The serologic tests should include the following laboratory studies:

  • Hepatitis B surface antigen (HBsAg)

  • Hepatitis B e antigen (HBeAg)

  • Hepatitis B core antibody (anti-HBc) immunoglobulin M (IgM)

  • anti-HBc IgG

  • Hepatitis B e antibody (anti-HBe)

  • hepatitis B virus (HBV) deoxyribonucleic acid (DNA)

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