How is renal failure treated in patients with acute liver failure (ALF)?

Updated: Jun 13, 2019
  • Author: Gagan K Sood, MD; Chief Editor: BS Anand, MD  more...
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Answer

Renal failure

Acute renal failure is a frequent complication in patients with acute liver failure and may be due to dehydration, hepatorenal syndrome, or acute tubular necrosis. [39] To preserve renal function, maintain adequate blood pressure, avoid nephrotoxic medications and nonsteroidal anti-inflammatory agents (NSAIDs), and promptly treat infections.

When dialysis is needed, continuous (ie, continuous venovenous hemodialysis [CVVHD]) rather than intermittent renal replacement therapy is preferred. Hemodialysis may significantly lower the mean arterial pressure such that cerebral perfusion pressure is compromised.


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