What is the role of platelet transfusion in the treatment of acute liver failure (ALF)?

Updated: Jun 13, 2019
  • Author: Gagan K Sood, MD; Chief Editor: BS Anand, MD  more...
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Answer

Platelet transfusions are not used until the platelet count is below 10,000/µL or if an invasive procedure is being done and the platelet count is less than 50,000/µL. Six to 8 units of random donor platelets (1 random donor unit platelet/10 kg) will increase the platelet count to greater than 50,000/µL. The platelet count should be checked after 1 hour and 24 hours. Transfused platelets survive 3-5 days.


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