What are the drug treatment options for treatment of acute liver failure (ALF)?

Updated: Jun 13, 2019
  • Author: Gagan K Sood, MD; Chief Editor: BS Anand, MD  more...
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Answer

Various medications may be necessary because of the variety of complications that may occur from fulminant hepatic failure. In specific cases, antidotes that effectively bind or eliminate toxins are essential.

The following medications may be used in the management of acute liver failure:

  • Antidotes (eg, penicillin G, silibinin, activated charcoal, N-acetylcysteine)

  • Osmotic diuretics (eg, mannitol)

  • Barbiturate agents (eg, pentobarbital, thiopental)

  • Benzodiazepines (eg, midazolam)

  • Anesthetic agents (eg, propofol)


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