Is surgical treatment of gastroesophageal reflux disease (GERD) more effective than medical treatment?

Updated: May 23, 2019
  • Author: Marco G Patti, MD; Chief Editor: BS Anand, MD  more...
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Answer

Several randomized clinical trials have challenged the benefits of surgery in controlling GERD. Lundell followed up his cohort of patients for 5 years and did not find surgery to be superior to PPI therapy. [46] Spechler found that, at 10 years after surgery, 62% of patients were back on antireflux medications. [47] A very rigorous, randomized study by Anvari et al reestablished surgery as the criterion standard in treating GERD. [48] The investigators showed that, at 1 year, the outcome and the symptom control in the surgical group was better than that in the medical group. [48]


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