What proton pump inhibitors (PPIs) are available for the treatment of gastroesophageal reflux disease (GERD)?

Updated: May 23, 2019
  • Author: Marco G Patti, MD; Chief Editor: BS Anand, MD  more...
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Answer

Available PPIs include omeprazole (Prilosec), lansoprazole (Prevacid), rabeprazole (Aciphex), and esomeprazole (Nexium). In November 2013, the FDA approved the first generic versions of rabeprazole sodium delayed-release tablets for the treatment of GERD in adults and adolescents ages 12 and up. In clinical trials, the most commonly reported adverse reactions to rabeprazole were sore throat, flatulence, infection, and constipation in adults, and abdominal pain, diarrhea, and headache in adolescents. [31]


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