What causes noninfectious forms of chronic gastritis?

Updated: Jun 07, 2019
  • Author: Akiva J Marcus, MD, PhD; Chief Editor: BS Anand, MD  more...
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Answer

Noninfectious forms of gastritis include the following:

  • Autoimmune gastritis

  • Chemical gastropathy- usually related to chronic bile reflux, NSAID and aspirin intake [51]

  • Uremic gastropathy

  • Chronic noninfectious granulomatous gastritis [35, 52, 53] – This may be associated with Crohn disease, sarcoidosis, Wegener granulomatosis, foreign bodies, cocaine use, isolated granulomatous gastritis, chronic granulomatous disease of childhood, eosinophilic granuloma, allergic granulomatosis and vasculitis, plasma cell granulomas, rheumatoid nodules, tumoral amyloidosis and granulomas associated with gastric carcinoma, gastric lymphoma, or Langerhans cell histiocytosis

  • Lymphocytic gastritis, including gastritis associated with celiac disease (also called collagenous gastritis) [36, 37, 38, 39, 54, 55] About 16% of patients with celiac disease have lymphocytic gastritis, which improves after a gluten-free diet, but there does not appear to be an association between lymphocytic gastritis and H pylori infection. [55] Chronic gastritis, whether active or inactive, does not appear to be affected by a gluten-free diet. [55]

  • Eosinophilic gastritis

  • Radiation injury to the stomach

  • Graft-versus-host disease (GVHD)

  • Ischemic gastritis [46]

  • Gastritis secondary to drug therapy (NSAIDs and aspirin)

Some patients have chronic gastritis of undetermined etiology or gastritis of undetermined type (eg, autistic gastritis [56] ).


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