What is the etiology of acute gastritis?

Updated: Jun 13, 2019
  • Author: Mohammad Wehbi, MD; Chief Editor: BS Anand, MD  more...
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Answer

Acute gastritis has a number of causes, including certain drugs; alcohol; bacterial, viral, and fungal infections; acute stress (shock); radiation; allergy and food poisoning; bile; ischemia; and direct trauma.

Causes of acute gastritis include the following:

  • Drugs - NSAIDs, such as aspirin, ibuprofen, and naproxen; cocaine; iron; colchicine, when at toxic levels, as in patients with failing renal or hepatic function; kayexalate; chemotherapeutic agents, such as mitomycin C, 5-fluoro-2-deoxyuridine, and floxuridine

  • Potent alcoholic beverages, such as whisky, vodka, and gin

  • Bacterial infections -H pylori (most frequent), H heilmanii (rare), streptococci (rare), staphylococci (rare), Proteus species (rare), Clostridium species (rare), E coli (rare), tuberculosis (rare), secondary syphilis (rare)

  • Viral infections (eg, CMV)

  • Fungal infections - Candidiasis, histoplasmosis, phycomycosis

  • Parasitic infection (eg, anisakidosis)

  • Acute stress (shock)

  • Radiation

  • Allergy and food poisoning

  • Bile: The reflux of bile (an alkaline medium is important for the activation of digestive enzymes in the small intestine) from the small intestine to the stomach can induce gastritis.

  • Ischemia: This term is used to refer to damage induced by decreased blood supply to the stomach. This rare etiology is due to the rich blood supply to the stomach.

  • Direct trauma


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