How does the prevalence of fatty liver disease vary by sex?

Updated: Apr 12, 2018
  • Author: Emily Tommolino, MD; Chief Editor: BS Anand, MD  more...
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Answer

Answer

Women develop more severe ALD more quickly and at lower doses of alcohol than men do. The increased susceptibility of females may be related to sex-dependent differences in the hepatic metabolism of alcohol, cytokine production, and the gastric metabolism of alcohol. In initial studies of NAFLD, the percentage of female patients was reported to be as high as 75%; however, in subsequent studies, the percentage fell to roughly 50%.


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