Which medications in the drug class Calcium channel blockers are used in the treatment of Esophageal Spasm?

Updated: Aug 07, 2019
  • Author: Ahmad Malas, MD; Chief Editor: BS Anand, MD  more...
  • Print
Answer

Calcium channel blockers

Calcium channel blockers reduce the amplitude of contractions. In nutcracker esophagus, calcium channel blockers effectively reduce the amplitude of contractions, but chest pain often is not reduced. Whether calcium channel blockers decrease the force of contraction of muscle or decrease the underlying stimulus is unknown.

Diltiazem (Cardizem, Cartia XT, Dilacor XR, Diltzac, Tiazac, Diltia XT)

Diltiazem is FDA approved for hypertension, vasospastic angina, and chronic stable angina. It decreases calcium ion flux across cell membranes in smooth muscle, thereby relaxing the vascular smooth muscle.


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!