How is achalasia diagnosed?

Updated: Dec 29, 2017
  • Author: Eric A Gaumnitz, MD; Chief Editor: Praveen K Roy, MD, AGAF  more...
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A thorough workup for achalasia includes an upper endoscopy. Biopsies should be obtained with any suspicion of a malignant process. If a suspicious lesion is found, imaging studies, including CT scan, MRI, and endoscopic ultrasound, should be obtained as indicated. In 50% of patients, the pathology is adenocarcinoma of the gastroesophageal junction. Other causes for pseudoachalasia include other malignancies, mechanical obstruction (eg, neurofibromatosis, pancreatic pseudocyst), and infiltrative diseases (eg, amyloidosis, sphingolipids, eosinophilic gastritis, sarcoidosis).

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