When is a direct antiglobulin test (DAT) indicated?

Updated: Jun 25, 2020
  • Author: Julie Katz Karp, MD; Chief Editor: Jun Teruya, MD, DSc, FCAP  more...
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The direct antiglobulin test (DAT) is valuable in the diagnosis of the following: [4]

  • Autoimmune hemolytic anemia

  • Drug-induced immune hemolytic anemia

  • Hemolytic transfusion reactions due to alloantibodies

  • Hemolytic disease of the fetus and newborn

  • Systemic lupus erythematosus (in the absence of hemolytic anemia)

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