When is infliximab indicated in the management of Crohn disease?

Updated: Jul 26, 2019
  • Author: Leyla J Ghazi, MD; Chief Editor: Praveen K Roy, MD, AGAF  more...
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Answer

Infliximab is effective in patients who have refractory perianal and enterocutaneous fistulae. Current clinical practice is to give it 5 mg/kg by intravenous (IV) infusion at 0 weeks, 2 weeks, and 6 weeks, followed by maintenance IV infusions every 8 weeks. On average, the effect lasts for 12 weeks.


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