How is chronic diarrhea managed in Crohn disease?

Updated: Jul 26, 2019
  • Author: Leyla J Ghazi, MD; Chief Editor: Praveen K Roy, MD, AGAF  more...
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Answer

Chronic diarrhea in Crohn disease responds well to antidiarrheal agents such as loperamide (2-4 mg), diphenoxylate with atropine (1 tablet), and tincture of opium (8-15 drops). Such agents may be administered up to 4 times daily, but they should not be given to patients with active colitis, because of the risk of developing toxic megacolon.


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