How is systemic sepsis managed in Crohn disease?

Updated: Jul 26, 2019
  • Author: Leyla J Ghazi, MD; Chief Editor: Praveen K Roy, MD, AGAF  more...
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In general, localized and systemic sepsis do not occur in fistulae that originate in diseased bowel and involve other intra-abdominal organs or the skin. [7] However, the presence of sepsis necessitates the initiation of broad-spectrum antibiotic agents. Radiologic studies should be performed to rule out concomitant abscesses, which should be drained when present. In cases of persistent sepsis, the diseased bowel is generally excised, whether an abscess is present or not (see Surgical Intervention).

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