When is hospitalization indicated in the management of Crohn disease?

Updated: Jul 26, 2019
  • Author: Leyla J Ghazi, MD; Chief Editor: Praveen K Roy, MD, AGAF  more...
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Many patients with an exacerbation of Crohn disease can be treated on an outpatient basis. However, if a serious complication of Crohn disease (eg, obstruction, perforation, abscess, or hemorrhage) is a concern or if outpatient treatment fails, IV therapy (eg, corticosteroids, antibiotics, or total parenteral nutrition [TPN]) may be required, and hospitalization is warranted.

Patients should be examined on a regular basis, with the frequency of examination depending on the severity and activity of their disease. Follow-up laboratory workup and diagnostic testing should be performed regularly as needed to monitor the safety and success of therapy. Clinical and biochemical responses to treatment should be determined in the 12-week period after the initiation of therapy, and endoscopy or transmural responses to therapy should be evaluated in the 6 months after the start of therapy. [59]

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