What is the role of upper GI endoscopy in the diagnosis of Crohn disease?

Updated: Jul 26, 2019
  • Author: Leyla J Ghazi, MD; Chief Editor: Praveen K Roy, MD, AGAF  more...
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Upper GI endoscopy (or esophagogastroduodenoscopy [EGD]) with biopsy is helpful in differentiating Crohn disease from peptic ulcer disease induced by nonsteroidal anti-inflammatory drugs (NSAIDs) or Helicobacter pylori or from fungal and viral gastroenteritis in patients with upper GI tract symptoms. A history of ileocolic Crohn disease in a patient with unexplainable upper GI symptoms warrants an EGD.

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