How effective is an ileocolonoscopy in the assessment of Crohn disease?

Updated: Jul 26, 2019
  • Author: Leyla J Ghazi, MD; Chief Editor: Praveen K Roy, MD, AGAF  more...
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Answer

Ileocolonoscopy has a sensitivity of 74% and a specificity of 100% in the assessment of Crohn disease, leading to a positive predictive value of 100% as a diagnostic test. [45] When paired with small bowel imaging, the sensitivity of this pair of diagnostic tests is increased to 78%, with a continued positive predictive value of 100%. [45]

For patients with Crohn disease of the colon, magnifying endoscopy allows a more detailed view of the mucosal surface than conventional endoscopy does. In combination with chromoendoscopy (methylene blue), it is possible to analyze the surface staining pattern further to help identify neoplastic changes in situ and take targeted biopsies. [6, 25, 68, 69, 70]

For more information, see Colonoscopy.


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